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Alpha Varin Complex – Trial Summary for Hair Growth

Preliminary Clinical Results

Below is a summary of the results of a 180-day, 40-person National Institutes of Health identified clinical study on the Varin-rich hemp extract in our ALPHA VARIN™ Complex that is found in TricoMax™ Hair Serum for textured hair. This clinical trial was sponsored by Gregory L. Smith, MD, MPH and was conducted by John Satino, BS.

Dr. Smith is a medical doctor with expertise in how the human body’s endocannabinoid system regulates the various body systems, including hair growth. Mr. Satino is a clinical researcher with decades of experience developing and evaluating cutting edge hair growth products like Minoxidil and Finasteride. Both experts agree that ALPHA VARIN™ Complex is the most advanced and effective hair formula ever developed.


Phase 1 Human Clinical Trial

  • Study Type: Interventional (Clinical Trial)
  • Estimated enrollment: 40 participants
  • Allocation: Randomized
  • Primary Purpose: Treatment
  • Official Title: Androgenetic Alopecia Treatment Using Varin and Cannabidiol-rich Topical Hemp Oil A Case Series
  • gov Identifier: NCT04842383
  • Intervention Model: Parallel Assignment
  • Intervention Model Description: 40 subjects will be randomly assigned into two treatment groups, 500mg of cannabinoids per ounce and 1000mg of cannabinoids per ounce. The change in hair follicle numbers will be compared statistically between the two groups.
  • Masking: Double (Participant, Outcomes Assessor)
  • Masking Description: The participants in the study and the outcomes assessor on day 0 and day 180 will be prevented from having knowledge of which of the two strengths of cannabinoid topicals were used.
  • NIH-Identified Phase 1 human clinical trial sponsored by principal investigator, Gregory L. Smith, MD, MPH; and conducted under the guidance of researcher, John Satino, at the Laser Hair Center in Clearwater, FL. The clinical trial measured non vellus hair counts within a one-centimeter square of the subject’s area of most significant balding as marked by a tattoo.
  • Safety & Toxicity: No adverse reactions were reported by any study

Note:  Subjects utilized no hair loss treatments, including minoxidil and/or finasteride during the six months of the study.


Conducted by  John Satino, BS.

  • Trained in Chinese Acupuncture – 1969
  • Principal Developer Electro-Acupuncture US – 1971 Studied Biomedical Engineering Ohio State University Post graduate work, Wright State University, under Dr
  • Gerald Petrowsky, Biomedical Dept. (Reversing Leg Muscle atrophy in Spinal Cord Injuries, with Electronic Muscle Stimulation) – 1977
  • Research Director, Biotone Heart Pacemaker Development Division – 1979
  • Consultant to NASA’s Biomedical Dept., Kennedy Space Center, for the development of EMS to prevent leg muscle atrophy in space – 1983
  • Research Coordinator, Upjohn Pharmaceutical, Research & Development of Minoxidil (Rogaine) for hair regrowth – 1984
  • Research Coordinator, Merck Pharmaceutical Research & Development of Finasteride (Propecia) for hair regrowth – 1989
  • Medical Advisor to Lexington International, for FDA Clearance using Low Level Laser for hair regrowth Published International Journal of Cosmetic Surgery and Aesthetic Dermatology – 2003
  • Published National Hair Journal (Laser Wound Healing) – 2005
  • Memberships; New York Academy of Sciences, American Hair Loss Council, Society for Laser Medicine and Surgery, Laser Institute of America, International Society of Hair Restoration Surgeons
  • Laser Safety Officer, Lumenis Laser Company
  • Past CEO Biostem US (Publicly Traded Regenerative Medicine Company ) – 2005
  • Presently, Clinic Director, Laser Hair & Scalp Clinics, Clearwater, FL.

Sponsored By: Gregory L. Smith, MD, MPH

  • Residency Trained, Board-Certified in Preventive Medicine and Occupational Medicine
  • Rush Medical College, Chicago, Illinois Medical Doctor (MD)
  • Harvard School of Public Health, Boston, Massachusetts Masters of Public Health (MPH)
  • William Beaumont Army Medical Center, El Paso, Texas Flexible Internship – May 1983
  • Walter Reed Army Medical Center, Washington, D.C. Residency in General Preventive Medicine – June 1985
  • Partial List of Publications/Presentations:
  • Hair Regrowth with Cannabidiol (CBD)-rich Hemp Extract – A Case Series, Cannabis 4: 53-59, 2021 Fast Facts: Medical Cannabis and Opioid Weaning (220 pages), Springer Press, January 2020 Tetrahydrocannabivarin and Endocannabinoid Energy Metabolism, Insurance Medical Directors Annual Meeting, Amsterdam, October 2019
  • CBDplus – THCV – Weight Loss, Anti-aging, Blood Sugar and Lipid Control (171 pages) – KDP Publishing, October 2018
  • Actuarial Issues with Medical Cannabis Use, American Academy of Insurance Medicine, Seattle, WA, October 2018
  • Antioxidant Nutraceuticals: Preventive and Healthcare Applications (414 pages) Chapter 14 – CRC Press, April 2018
  • CBD: What You Need to Know (245 pages) – KDP Publishing, August 2017


A complete CB1 Receptor Antagonist

Blocking the human body’s CB1 receptors with ALPHA VARIN Complex™ results in (1) the stimulation of keratinocytes witch results in hair shaft elongation and (2) stimulation of matrix cells which results in thickening of the hair shaft. ALPHA VARIN Complexalso stimulates the TRPV1 receptor which lengthens the duration of time the hair shaft is in the telogen, or resting phase, of the growth cycle. The results in this clinical trial show increases in hair shaft thickness, hair shaft health, and hair counts in the areas of balding.


Hair Thickness and HealthHair Thickness and Health

Using ALPHA VARIN Complex study participants experienced significantly thicker and healthier hair.



Hair Counts at Day 0Hair Counts at Day 0

100% of study participants using ALPHA VARIN Complex experienced at least 105% increase in new nonvellus hair counts over the 180 day trial.



Hair Counts at Day 180Hair Counts at Day 180

Multiple study participants using ALPHA VARIN Complex experienced an 800%+ increase in new nonvellus hair counts with an average increase per study participant of 371%.



Artists rendering

of study findings

– not to scale



Participants used the All-Natural ALPHA VARIN ComplexTM  for 180 days. On average, study participants experienced 371% increase in new nonvellus hair counts as measured in the test-count area. The test-count area was a 1cm- square area marked with a tattoo and located in the area of most significant balding.



Participants used the All-Natural ALPHA VARIN Complex TM for 180 days. In addition to the significant increases in new novellus hair counts, study participants also experienced a significantly thicker core of the hair shaft and improved healthy appearance of the hair.


Shaft Thickening
Day 1 Hair Count
Day 180 Hair Count


Artist’s rendering of study findings not to scale.



100%100% of study participants using ALPHA VARIN Complex experienced at least 105% increase in new non vellus hair counts


91%  Upon completion of the study, participants indicated an average 91% satisfaction with the ALPHA VARIN      Complex.


On average, study participants using ALPHA VARIN Complex experienced a 371% increase in new non vellus hair counts as measured in the test-count area.


Study participants using ALPHA TM VARIN Complex experienced significantly improved hair thickness and health.

23% of study participants saw new nonvellus hair count increases of at least 8X
31% of study participants saw new nonvellus hair count increases of at least 5X
62% of study participants rated ALPHA VARIN™ a perfect 10 out of 10.


These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.


ALPHA VARIN Complex is 100% All-Natural and can be used safely with confidence.

Virtually all hair restoration products on the market are made from synthetic pharmaceuticals with a multitude of potential side- effects and warnings for use.

All-Natural ALPHA VARIN hair products are powered by BEVARIN Wellness’ proprietary ALPHA VARIN Complex and completely block the body’s CB1 receptors leading to hair growth and restoration. For best results and to maintain hair increases, continued use of the product is recommended.

See trial results



Trial Summary for Hair Growth

Preliminary Clinical Results







































These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.




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